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Flurazepam is a benzodiazepine (ben-zoe-dye-AZE-eh-peen) similar to Valium. Flurazepam affects chemicals in the brain that may be unbalanced in people with sleep problems (insomnia). Flurazepam is used to treat symptoms of insomnia, such as trouble falling or staying asleep.


Flurazepam (marketed under the brand names Dalmane and Dalmadorm) is a drug which is a benzodiazepine derivative. It possesses anxiolytic, anticonvulsant, hypnotic, sedative and skeletal muscle relaxant properties. It produces a metabolite with a long half-life, which may stay in the bloodstream for days. Flurazepam was patented in 1968 and came into medical use the same year. Flurazepam, developed by Roche Pharmaceuticals was one of the first benzo hypnotics (sleeping pills) to be marketed.
Flurazepam is officially indicated for mild to moderate insomnia and as such it is used for short-term treatment of patients with mild to moderate insomnia such as difficulty falling asleep, frequent awakening, early awakenings, or a combination of each. Flurazepam is a long-acting benzodiazepine and is sometimes used in patients who have difficulty maintaining sleep. Intermediate half-life benzodiazepines are also useful for patients with difficulty in maintaining sleep (e.g. loprazolam, lormetazepam, temazepam). The most common adverse effects are dizziness, drowsiness, light-headedness, and ataxia. Flurazepam has abuse potential and should never be used with alcoholic beverages or any other substance that can cause drowsiness. Addictive and possibly fatal results may occur. Flurazepam users should only take this drug strictly as prescribed, and should only be taken directly before the user plans on sleeping a full night. Next-day drowsiness is common and may increase during the initial phase of treatment as accumulation occurs until steady-state plasma levels are attained.


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